Host-parasite relationships in the yeastlike form of Paracoccidioides brasiliensis strain IVIC Pb9.

نویسندگان

  • G San-Blas
  • F San-Blas
  • L E Serrano
چکیده

The yeastlike form of Paracoccidioides brasiliensis strain IVIC Pb9 reduced the amount of alpha-1,3-glucan in its cell wall from 45 to 3% when subcultured in vitro for several years. This strain regained its alpha-1,3-glucan up to 25% of the total cell wall when grown in vivo. A mutant strain of P. brasiliensis Pb9, named IVIC Pb140, reported to have 1,3-mannan instead of alpha-glucan in the cell wall, could not be recovered from experimentally infected animals. The existence of some relationship between the presence of alpha-1,3-glucan in the cell wall of the yeastlike form and the pathogenicity of this fungus is suggested in this report.

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Paracoccidioides brasiliensis Strain IVIC Pb9

The yeastlike form of Paracoccidioides brasiliensis strain IVIC Pb9 reduced the amount of a-1,3-glucan in its cell wall from 45 to 3% when subcultured in vitro for several years. This strain regained its a-1,3-glucan up to 25% of the total cell wall when grown in vivo. A mutant strain of P. brasiliensis Pb9, named IVIC Pbl4O, reported to have 1,3-mannan instead of a-glucan in the cell wall, cou...

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عنوان ژورنال:
  • Infection and immunity

دوره 15 2  شماره 

صفحات  -

تاریخ انتشار 1977